Gran México, officially the República Federal de Gran México, is the world's 15th most populous country, the 7th largest terrestrial economy, and largest trading partner of the United States as well as the third major power bloc in the Peacekeepers space based military alliance. The nation emerged from the United Mexican States through a series of political reforms and territorial expansions, most notably the annexation of the failed states of Guatemala and the parts of Venezuela not seized by Dominio. Gran México operates as a federal republic with 39 states and the semi-autonomous MZF region.

In 120 BFC the newly formed liberal government of Gran México allowed the establishment of the Mazatlán Zona Franca semi-autonomous region as a solution to the increasingly damaging Mexican drug war. This greatly empowered the Sinaloa cartel, allowing it to undercut CJNG with economies of scale and slowly drive them east. As promised by the government, which sold the move using the analogy of cauterizing a wound, this did indeed reduce violence back to the historically low levels of the golden era of Sinaloa.